Igiciro kinini cyinshi 100% Amavuta meza ya Forsythiae Amavuta ya Fructus Yorohereza Aromatherapy Eucalyptus globulus

ibisobanuro bigufi:

Forsythia suspensa(Thunb.) Vahl. (Family Oleaceae) ni igihuru cyimitako, imbuto zacyo zikoreshwa nka TCM izwi cyane "Forsythiae Fructus" (FF) (连翘 mu gishinwa). Ibiranga TCM biranga FF byavuzwe mu ncamake nk'uburakari mu buryohe, hamwe n'ubukonje bworoheje n'ibihaha, umutima cyangwa intestinum meridian ikwirakwizwa (Komisiyo ya Pharmacopoeia ya PRC, 2015), ibyo biranga bihwanye no kuranga TCM yo kurwanya inflammatory, nk'uko Chen abitangaza na Zhang (2014). Mu bimera bya Shennong, FF yakoreshejwe mu kuvura pyrexia, gutwika, gonorrhea, karbuncle na erysipelas (Cho et al., 2011). Ubwoko bubiri bwa FF burahari, imbuto zicyatsi kibisi zeze zitwa "Qingqiao" naho umuhondo wera rwose witwa "Laoqiao". Byombi bikora nkisoko yemewe ya FF, nyamara, Qingqiao ikoreshwa cyane mubitabo bya TCM (Jia et al., 2015). Ibice byingenzi bitanga umusaruro wa FF ni Hebei, Shaanxi, Shanxi, Shandong, Anhui, Henan, Hubei, Jiangsu (bihingwa) n'Intara za Sichuan (Ubuyobozi bukuru bwa Flora y'Ubushinwa, 1978).

Mu gitabo cy’Abashinwa Pharmacopoeia 2015, hateguwe urutonde rw’imiti 114 y’Abashinwa irimo FF, urugero nk'umuti wo mu kanwa wa Shuanghuanglian, ibinini bya Yinqiao Jiedu, ibinini bya Niuhuang Shangqing, n'ibindi (Komisiyo ya Pharmacopoeia ya PRC, 2015). Ubushakashatsi bugezweho bugaragaza anti-inflammatory (Kim et al., 2003), antioxydeant (CC Chen et al., 1999), antibacterial (Han et al., 2012), kurwanya kanseri (Hu et al., 2007), anti -virus (Ko et al., 2005), anti-allergie (Hao et al., 2010), ingaruka za neuroprotective (S. Zhang et al., 2015),n'ibindiNubwo imbuto gusa zikoreshwa nka TCM, ubushakashatsi bumwe bwerekanye ingaruka za phytochemie ningaruka za farumasi yibibabi (Ge et al., 2015, Zhang et al., 2015), indabyo (Takizawa et al., 1981) n'imbuto (Zhang et al ., 2002) yaF. guhagarika. Kubwibyo, ubu turatanga incamake ya sisitemu yamakuru aboneka yaF. guhagarika, harimo imikoreshereze gakondo, ibimera, phytochemie, farumasi, uburozi, imiti ya farumasi no kugenzura ubuziranenge. Na none, icyerekezo gishoboka cyubushakashatsi kiraganirwaho.

Igice

Imikoreshereze gakondo

Mu nyandiko za kera z’ibimera by’Abashinwa, FF yanditse ko ari ingirakamaro mu kuvura fistula, scrofula, karbuncle, ibisebe bibi, ibibyimba byo mu nda, ubushyuhe n’uburozi (ibyatsi bya Shennong, Bencao Chongyuan, Bencao Zhengyi, Zhenglei Bencao). Dukurikije ibya kera bya kera, iki cyatsi cy’ubuvuzi gifite akamaro kanini mu gukuraho ubushyuhe bwumuyoboro wumutima no kurekura ubushyuhe-ubushyuhe bwimpyiko nigifu. Nubuvuzi kandi bwo kuvura stranguria, edema, qi stagnancy hamwe namaraso

Botany

F. guhagarika. Ifite interode yuzuye hamwe no gukwirakwiza amashami afite ibara ry'umuhondo-umukara cyangwa imvi-umukara. Amababi mubisanzwe aroroshye, ariko rimwe na rimwe 3-foliolate. Ibibabi byamababi ni ovate, ovate yagutse, cyangwa elliptike-ovate na 2-10 × 1.5-5 cm2 z'ubunini hamwe nu ruziga ruzengurutse umusingi hamwe na apex ikaze. Impande zombi zamababi ni icyatsi, glabrous hamwe cyane cyangwa byoroshye

Phytochemie

Muri iki gihe, ibice 237 byabonetse muriF. guhagarika, harimo 46 lignans (1-46), glycoside ya fenylethanoide 31 (47–77), flavonoide 11 (78-88), terpenoide 80 (89-168), inkomoko 20 ya cyclohexylethanol (169–188), alkaloide esheshatu (189–194) ), steroidale enye (195–198) hamwe nibindi 39 (199-27). Muri byo, ibice bibiri (21-22) byitaruye indabyo zaF. guhagarika, Ibice 19 (94–100, 107–111, 115–117, 198, 233-23) bitandukanije namababi yaF. guhagarika, ibice bine

Ingaruka zo kurwanya inflammatory

Ibikorwa byo kurwanya inflammatory ya FF ishyigikira ingaruka zayo zo gukuraho ubushyuhe (Guo et al., 2015). Gutwika ni igisubizo cyumubiri kubitera kwandura, allergique, cyangwa imiti (Lee et al., 2011). Ifite uruhare mu iterambere ryindwara zidakira, nkindwara zuruhu, allergie, na kanseri,n'ibindiFF ni imwe muri TCM ifite imbaraga zo kurwanya anti-inflammatory, ikoreshwa cyane mubitero bidakira kandi bikaze. Ibikorwa byo kurwanya inflammatory FF byashyizwe ku mwanya wa gatanu muri 81 zapimwe TCM (70% Ethanol

Uburozi

Kugeza ubu, nta raporo yerekana uburozi bwa FF. Imiti ya buri munsi ya FF isabwa kuba 6-15 g (Komisiyo ya Pharmacopoeia ya PRC, 2015). Raporo zingenzi zerekanye ko nta burozi bukabije bw’amazi cyangwa Ethanol ikuramo amababi yaF. guhagarikamu mbeba, ndetse no ku gipimo cya buri munsi cya 61,60 g / kg (Ai et al., 2011, Hou et al., 2016, Li et al., 2013). Han n'abandi. (2017) yatangaje ko nta burozi bukabije bwa phillyrin (uhereye ku mababi yaF. suspensa)imbeba za NIH (18.1 g / kg / kumunsi, po, iminsi 14) cyangwa oya

Imiti ya farumasi

Li n'abandi. yerekanye icyiciro icyenda I metabolite ya phillyrin mu nkari z'inkari z'imbeba kandi yerekanaga inzira zishoboka zo guhinduranya imbeba. Phillyrin yabanje gushiramo hydrolyz muri phillygenin hanyuma ahindurwamo izindi metabolite yiganjemo methylation, demethylation, dehydroxylation hamwe nuburyo bwo gufungura impeta (Li et al., 2014c). H. Wang n'abandi. .

Kugenzura ubuziranenge

Kugenzura ubuziranenge bwa FF, Pharmacopoeia yo mu Bushinwa itanga imiterere ya morphologique, microscopique na TLC hiyongereyeho icyemezo cya HPLC. Icyitegererezo cya FF cyujuje ibyangombwa kigomba kuba kirimo 0.150% ya phillyrine (Komisiyo ya Pharmacopoeia ya PRC, 2015).

Nyamara, ikimenyetso kimwe cyuzuye, phillyrin, gisa nkigihagije kugirango dusuzume ubuziranenge bwa FF. Vuba aha, ibice bitandukanye bya bioactive muri FF byasuzumwe na chromatografiya itandukanye, electrophorei, MS na NMR, nka

Umwanzuro n'ibitekerezo bizaza

Iri suzuma rivuga muri make amakuru yuzuye yerekeye imikoreshereze gakondo, ibihingwa, phytochemie, ingaruka za farumasi, uburozi, imiti ya farumasi no kugenzura ubuziranenge bwaF. guhagarika. Mu nyandiko za kera z’ibimera n’ibishinwa hamwe na Pharmacopoeia yo mu Bushinwa, FF ikoreshwa cyane mu gukuraho ubushyuhe no kwangiza. Kugeza ubu, ibice birenga 230 byatandukanijwe kandi byamenyekanye muri iki cyatsi. Muri byo, lignans na fenylethanoid glycoside bifatwa nkibiranga na bioactive

Ibisobanuro bya TCM

Yin: “Yin” ni imwe mu mbaraga ebyiri zuzuzanya zinyuranye za kamere, ukurikije uko Abashinwa ba kera bubaka isanzure. “Yin” irangwa no gutinda, yoroshye, gutanga umusaruro, gukwirakwira, imbeho, itose cyangwa ituze, kandi ifitanye isano n'amazi, isi, ukwezi, uburinganire n'ijoro.

Ikibazo: Mu magambo acupuncture, "qi" n "imbaraga zubuzima". Nisoko yimikorere yose mumubiri, kurinda igitero cyumubiri, isoko yibikorwa byose bya metabolike, iteganya gufata ingirangingo

Gushimira

Uyu murimo washyigikiwe nu mushinga uhuriweho n’ubushakashatsi bwa siyanse wa Beijing hamwe n’ubumenyi bw’icyiciro cya kabiri cya kaminuza - Ubushakashatsi bw’ikoranabuhanga n’ikoreshwa ry’isuzuma ry’umutekano ry’ibikoresho by’imiti by’ubushinwa by’ubumara bishingiye ku bigize imiti n'ibiranga zebrafish.

FOB Igiciro:US $ 0.5 - 9,999 / Igice

Min.Umubare w'Itegeko:100 Igice / Ibice

Ubushobozi bwo gutanga:10000 Igice / Ibice buri kwezi

Ohereza imeri kuri twe

Ibicuruzwa birambuye

Ibicuruzwa

Ibyerekeye Ethnopharmacological

Forsythiae Fructus (yitwa Lianqiao mu Gishinwa), imbuto zaForsythia suspensa(Thunb.) Vahl, ikoreshwa nk'ubuvuzi gakondo mu Bushinwa, Ubuyapani na Koreya. Bikunze gukoreshwa mu kuvura pyrexia, gutwika,gonorrhea,carbunclenaerysipelas. Ukurikije ibihe bitandukanye byo gusarura, Forsythiae Fructus irashobora gushyirwa mubice bibiri, aribyo Qingqiao na Laoqiao. Imbuto z'icyatsi zitangiye kwera zegeranijwe nka Qingqiao, mugihe imbuto z'umuhondo zeze neza zegeranijwe nka Laoqiao. Byombi bikoreshwa mubuvuzi. Iri suzuma rigamije gutanga incamake itunganijwe yaF. guhagarika(Forsythia suspensa(Thunb.) Vahl) no kwerekana isano iri hagati yimikoreshereze gakondo naibikorwa bya farumasikugirango dutange inspiration kubushakashatsi buzaza.

Ibikoresho nuburyo

Ibisobanuro byose bijyanyeF. guhagarikayashakishijwe na Scifinder akura mububiko bwa siyanse harimo Springer, Science Direct, Wiley, Pubmed na China Knowledge Resource Integrated (CNKI). Hashakishijwe kandi ibitabo byaho ndetse n'ibitabo.

Ibisubizo

Dukurikije inyandiko za kera z’ibimera n’ibishinwa hamwe na Pharmacopoeia yo mu Bushinwa, Forsythiae Fructus yigaragaza cyane ingaruka zo gukuraho ubushyuhe no kwangiza muriTCMimiti. Mu bushakashatsi bugezweho, ibice birenga 230 byatandukanijwe kandi byamenyekanye kuvaF. guhagarika. 211 Muri bo bitandukanije n'imbuto.Lignansna fenylethanoidglycosidezifatwa nkibiranga kandi bikora bigize iki cyatsi, nka forsythiaside, phillyrin,rutinna Phillygenin. Berekanye anti-inflammatory, antioxidant, antibacterial, anti-virusi, anti-kanseri n'ingaruka zo kurwanya allergie,n'ibindiKugeza ubu, nta raporo ivuga ku burozi bwa Forsythiae Fructus, nubwo uburozi buke bwa forsythiaside bwatangajwe mu bitabo byaho. Ugereranije na Laoqiao, Qingqiao irimo urwego rwo hejuru rwa forsythiaside, forsythoside C, cornoside,rutin, Phillyrin,aside asidenaaside ya chlorogenen'urwego rwo hasi rwa rengyol,β-glucose na S-guhagarikamethyl ether.

Umwanzuro

Ibikorwa byo gukuraho ubushyuhe bwa Forsythiae Fructus bishingiye kumiterere yo kurwanya inflammatory na antioxydeant ya lignans na fenylethanoidglycoside. Ingaruka zangiza ziterwa na antibacterial, antiviral na anti-kanseri ya Forsythiae Fructus. Ubuvuzi gakondo bw'Abashinwa (TCM) buranga Forsythiae Fructus (uburyohe busharira, imiterere ikonje gato na meridian y'ibihaha) byashyigikiraga ingaruka zikomeye zo kurwanya inflammatory. Mubyongeyeho, bidasanzwe birwanya anti-inflammatory naubushobozi bwa antioxydeantya Forsythiae Fructus igira uruhare mu kurwanya kanseri kandineuroprotectiveibikorwa. Umubare munini wa lignans na fenylethanoid glycoside muri Qingqiao kurusha Laoqiao ushobora gusobanura ubushobozi bwiza bwa antioxydeant ya Qingqiao no gukoresha kenshi Qingqiao muriTCMimiti. Kubushakashatsi buzaza, nibindimuri vivoubushakashatsi nubushakashatsi bwubuvuzi birashishikarizwa kurushaho gusobanura isano iri hagati yimikoreshereze gakondo nuburyo bugezweho. Kubyerekeranye na Qingqiao na Laoqiao, bakomeje gutandukanwa nuburyo bwose bwo kugenzura ubuziranenge, kandi imiti n’imiti bivura hagati yabo bigomba kugereranywa.