Amavuta meza ya magnoliya asanzwe amavuta ya flos magnoliae yamavuta ya parufe
Magnoliae Flos ni ibikoresho bisanzwe bivura imiti muri Aziya. Ikoreshwa mukuvura sinusite, kunanuka kwizuru, hamwe nuruhu rwinshi. Kubera ko Magonlia Flos yasobanuwe nk'ibintu bihumura neza mu nyandiko za kera z'Abashinwa, twavuze ko amavuta ya ngombwa ashobora gukoreshwa mu kuvura indwara z'umubiri. Ingirabuzimafatizo ya Dendritic (DCs), ifatwa nkintego nyamukuru y’ubudahangarwa bw'umubiri kugira ngo igenzure ubudahangarwa bw'umubiri, igira uruhare runini mu kurwanya ubudahangarwa bw'umubiri. Muri ubu bushakashatsi, amavuta ya Magnoliae Flos (MFEO) yagabanije umusaruro wa cytokine TNF-α "uruhare =" kwerekana "style =" agasanduku-kangana: imipaka-agasanduku; kwerekana: umurongo; umurongo-uburebure: bisanzwe; intera-ijambo: ibisanzwe; kurengerwa-gupfunyika: bisanzwe; Umwanya-wera: nowrap; kureremba: nta; icyerekezo: ltr; ubugari bwa max: nta; uburebure-burebure: nta; ubugari bwa min: 0px; uburebure bwa min: 0px; umupaka: 0px; padi: 0px; margin: 0px; umwanya: isano; ”> α
, IL-6, na IL-12p70 muri lipopolysaccharide (LPS) -bigereranya DC. Yahagaritse kandi ibimenyetso byerekana hejuru ya MHC II, CD80, na CD86 muri DC ikangurwa na LPS. Icyitegererezo cy’inyamaswa cyerekanye ko 2,4-Dinitro-1-fluorobenzene (DNFB) itera umubyibuho ukabije wabujijwe nyuma yo kuvurwa na MFEO. Byongeye kandi, MFEO yabujije kwinjira muri selile T mumatwi yimbeba zatewe na DNFB. Kugirango ushakishe ibinyabuzima byacyo, ibice bya MFEO byasesenguwe hakoreshejwe gazi chromatografiya (GC) na GC-mass spectrometry. Ibisubizo byagaragaje ko ibice byingenzi muri MFEO ari camphor na 1.8-cineole. Ibindi bioassay ya DC yemeje ko ibyo bikoresho byahagaritse cyane umusaruro wa cytokine muri DC iterwa na LPS. Kubwibyo, twerekanye ko MFEO yerekana ingaruka zo gukingira byombimuri vivonamuri vitro, na camphor na 1.8-cineole birashobora kuba ibice byingenzi bishinzwe ubushobozi bwikingira. Ibyavuye mu bushakashatsi byerekana ko MFEO ifite ubushobozi bwo gutezwa imbere nka immunosuppressant nshya y’indwara zikabije.